Tesofensine

Tesofensine is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) originally researched for Parkinson's and Alzheimer's, now adopted as an anti-obesity drug.

Weight Loss Benefits

• Appetite suppression
• Increases energy
• Improves blood sugar levels and insulin sensitivity
• Increases resting energy expenditure and fat oxidation
• Targets abdominal fat
• Reduces cravings

Additional Benefits

• Helps preserve cognitive health
• Increases BDNF, triggering antidepressant effects
• Functions as anti-anxiety agent
• Increases serotonin, noradrenaline, and dopamine
• May improve sexual function
• Advised for binge eating disorder
• Improves ADHD symptoms
• Treats serotonin-deficient insomnia
• May help treat alcohol addiction

Possible Side Effects

• Dry mouth, slight increase in blood pressure/pulse, constipation, diarrhea, nausea, headache, insomnia, mood effects

Contraindications & Warnings

• Do not use if pregnant or nursing
• Do not use with preexisting cardiovascular disease, uncontrolled hypertension, arrhythmias
• Do not use with uncontrolled psychiatric disorders
• Do not use with MAOIs
• Do not use with glaucoma
• Do not use with ANY serotonin agent (SSRIs, SNRIs, tricyclic antidepressants, MAOIs, etc.) — risk of Serotonin Syndrome

TESOFENSINE: 500MCG — DOSING

Tesofensine has a very long half-life; one pill per day is sufficient.