Semax Cartridge Refill

Semax is a synthetic peptide that is an analog of adrenocorticotropic hormone (ACTH). It has been studied for its neuroprotective, cognitive-enhancing, and antidepressant effects. Semax stimulates the release of brain-derived neurotrophic factor (BDNF), a protein that promotes neuron growth and survival, and modulates neurotransmitter levels including dopamine, serotonin, and norepinephrine. It offers nootropic, neuroprotective, and neurorestorative benefits.

Benefits

• Memory enhancement: Participants using Semax made 31% more correct responses than the control group on memory tests
• Neuoprotection: Shields neurons from stroke, trauma, or neurodegenerative disease damage
• Antidepressant effects: Reduces anxiety and depression in animal studies
• Supports neuron survival and promotes synaptic growth and neuroplasticity
• Helps neurons adapt to injury or environmental change
• Protects the optic nerve and may be helpful for related disorders
• Improves trophic supply of the brain (supports brain network connectivity)
• May help manage ADHD symptoms
• Inhibits enzymes that degrade enkephalins and regulatory peptides
• May support recovery from opioid or alcohol withdrawal
• Shows improvement in non-proliferative diabetic neuropathy
• Potential for pain relief

Possible Side Effects

• Headache
• Mild dizziness or light-headedness
• Very rare risk of slight increase in blood sugar levels
• Injection site reaction (redness, swelling, and/or itching)

Warnings and Precautions

Semax modulates central nervous system signaling pathways, including dopaminergic, serotonergic, and neurotrophic (e.g. BDNF-related) mechanisms. Use caution in individuals with a history of:

• Anxiety disorders
• Panic disorder
• Bipolar disorder (including hypomania or mania)
• Psychotic disorders or schizophrenia

Potential adverse neuropsychiatric effects may include agitation, irritability, restlessness, or insomnia. Discontinue use if clinically significant psychiatric symptoms emerge or worsen.

Contraindications

• Do not use if you determine that you are hypersensitive to Semax- this is an indication of an allergic reaction
• Do not use if pregnant or breastfeeding
• Avoid in individuals with endocrine instability
• Use caution if you have a severe psychiatric disorder (particularly active psychosis, manic episodes, or uncontrolled anxiety)- the stimulatory/neuroactive effects could worsen mood/psychiatric state
• Safety profile is not well established in children and pediatric use should be avoided