Originally developed as a medication to treat Type-2 Diabetes, Semaglutide has been adopted as an effective tool to combat obesity in recent years. It is a glucagon-like peptide-1 (GLP-1) agonist, which mimics the GLP-1 hormone. GLP-1 is a hormone in the gut that is released in response to eating. In higher amounts, it interacts with the brain in a manner that suppresses appetite and causes a lasting feeling of fullness.
Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight: 4113.64 g/mol
Purity: 99%
For research purposes only. This product is supplied exclusively for scientific laboratory research and analytical purposes. It is not intended for human or animal use, and must not be misused in any way that contravenes MHRA regulations or applicable laws.
Originally developed as a medication to treat Type-2 Diabetes, Semaglutide has been adopted as an effective tool to combat obesity in recent years. It is a glucagon-like peptide-1 (GLP-1) agonist, which mimics the GLP-1 hormone. GLP-1 is a hormone in the gut that is released in response to eating. In higher amounts, it interacts with the brain in a manner that suppresses appetite and causes a lasting feeling of fullness.
After 68 weeks, half of clinical trial participants lost 17% of their initial body weight, and another third lost 20% with improved diet and exercise. Many individuals regained weight after stopping the medication, which highlights the importance of long-term strategy.
Other Benefits
Reduces risk of major cardiovascular events (death, heart attack, or stroke) in adults with heart disease
Potent anti-inflammatory effects
Helps reduce amyloid protein buildup in the brain (linked to Alzheimer’s)
Shown potential in treating substance use disorders by reducing cravings
Improves blood sugar regulation
Lowers risk of COVID-19-related complications
Fewer outbreaks of hidradenitis suppurativa
Side Effects
Of all GLP-1 medications, Semaglutide has one of the highest rates of side effects. These may include:
Nausea
Diarrhea
Vomiting
Constipation
Abdominal pain
Headache
Fatigue
Dizziness
Sulfur-smelling burps
Gas and bloating
Heartburn
Runny nose
Sore throat
Less Common but More Serious Side Effects
Thyroid tumors and/or cancer
Inflammation of the pancreas
Gallbladder disease
Gastroperesis (stomach paralysis)
Kidney failure
Changes in vision (esp. for diabetics)
Depression or suicidal ideation
Increased heart rate
Hypoglycemia (especially if combined with insulin or sulfonylureas)
Contraindications
Do NOT take Semaglutide if:
You are allergic or hypersensitive to any ingredients
You are pregnant or breastfeeding
You have thyroid disease
You or your family has a history of medullary thyroid cancer
You have Multiple Endocrine Neoplasia Syndrome Type 2 (MEN 2)
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