5-Amino-1MQ is a research compound that works by inhibiting the enzyme nicotinamide N-methyltransferase (NNMT), which in turn helps increase cellular NAD+ levels.
This mechanism leads to various potential benefits, primarily centered on metabolic enhancement and supporting fat loss, as indicated by preclinical studies.
For research purposes only. This product is supplied exclusively for scientific laboratory research and analytical purposes. It is not intended for human or animal use, and must not be misused in any way that contravenes MHRA regulations or applicable laws.
5-Amino-1MQ is a small molecule compound designed to inhibit the enzyme NNMT (nicotinamide N-methyltransferase), which plays a key role in metabolic regulation and fat cell activity. By suppressing NNMT, 5-Amino-1MQ increases NAD⁺ levels and helps to accelerate energy metabolism, support healthy body composition, and reduce fat mass—especially visceral fat. It has gained attention for its potential to improve insulin sensitivity, mitochondrial function, and cellular repair, making it a popular option in fat loss, longevity, and athletic performance protocols.
Key Benefits
Promotes rapid fat loss without muscle breakdown
Inhibits fat cell growth and reduces existing fat deposits
Boosts NAD⁺ levels and mitochondrial energy production
Improves insulin sensitivity and glucose tolerance
Enhances physical endurance and energy
Supports cellular longevity and anti-aging effects
May assist in reducing inflammation and oxidative stress
Mechanism of Action
5-Amino-1MQ works primarily by:
NNMT Inhibition: Suppresses the enzyme responsible for downregulating energy metabolism in fat cells
NAD⁺ Elevation: Increases intracellular NAD⁺, enhancing mitochondrial function and energy production
Mitochondrial Optimization: Promotes thermogenesis and lipid oxidation via improved mitochondrial efficiency
The result is an upregulation of cellular metabolism, reduced fat accumulation, and improved lean body mass.
Possible Side Effects
Common (usually temporary and mild):
Headache
Mild fatigue
Digestive discomfort (bloating, nausea)
Mild increase in heart rate
Rare:
Skin irritation or redness at injection site
Dizziness or jitteriness
Temporary sleep disturbances
Side Effect Management
Stay hydrated and eat balanced meals during the protocol
Reduce dosage if fatigue or nausea occurs
Use smaller split doses if needed to increase tolerance
Contraindications
Do NOT use 5-Amino-1MQ if:
You are pregnant or breastfeeding
You have uncontrolled cardiovascular conditions
You have liver or kidney impairment
You are allergic to any excipients or BAC
You are on medications that alter NAD metabolism without physician oversight
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