SS-31, also known as Elamipretide, Bendavia, or MTP-131, is a synthetic peptide that targets and improves mitochondrial function. Mitochondria generate ATP (the body’s primary energy molecule), regulate cellular homeostasis, and impact nearly all physiological systems. SS-31 is a mitochondrial-targeted antioxidant with extensive therapeutic potential: mitigating oxidative stress, suppressing inflammation, maintaining mitochondrial health, and preventing cellular apoptosis.
It has several advantages over natural antioxidants and plays a key role in treating mitochondrial dysfunction-related disorders.
Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Weight: 639.8 g/mol
Purity: ≥99%
Sequence: D-Arg-Dmt-Lys-Phe-NH₂
For research purposes only. This product is supplied exclusively for scientific laboratory research and analytical purposes. It is not intended for human or animal use, and must not be misused in any way that contravenes MHRA regulations or applicable laws.
SS-31, also known as Elamipretide, Bendavia, or MTP-131, is a synthetic peptide that targets and improves mitochondrial function. Mitochondria generate ATP (the body’s primary energy molecule), regulate cellular homeostasis, and impact nearly all physiological systems. SS-31 is a mitochondrial-targeted antioxidant with extensive therapeutic potential: mitigating oxidative stress, suppressing inflammation, maintaining mitochondrial health, and preventing cellular apoptosis.
It has several advantages over natural antioxidants and plays a key role in treating mitochondrial dysfunction-related disorders.
Benefits
Increased energy (most potent energy-boosting peptide available)
Neutralizes free radicals and reverses oxidative stress damage
Anti-aging
Anti-inflammatory (including neuroinflammation)
Supports memory and cognition
Antifibrotic
Beneficial for kidney disease (activates AMPK pathway)
Fights insulin resistance
May prevent or mitigate symptoms of:
Cardiovascular disease
Neurodegenerative conditions
Asthma and COPD
Age-related macular degeneration
Cancer
Barth syndrome
Primary mitochondrial myopathy
Duchenne muscular dystrophy
Friedrich’s ataxia
Possible Side Effects
Injection site irritation (redness, swelling, and/or itching)
Gas
Gastrointestinal upset
Headache
Dizziness
Signs of an allergic reaction include: fast, erratic heartbeat; profuse sweating; shortness of breath; confusion; severe weakness; loss of coordination; stiff muscles and high fever; eye symptoms including blurred vision, tunnel vision, eye pain, swelling of the eyes, seeing halos around lights
Contraindications
Do not use if pregnant or breastfeeding
Do not use if hypersensitive to mitochondrial-targeted compounds
Stacking Suggestions
MOTS-C – run SS-31 before a MOTS-C cycle for maximum mitochondrial optimization. SS-31 primes the mitochondria, MOTS-C boosts cellular adaptation and metabolic health (Follow standard protocol for 10-14 days prior to start of MOTS-C protocol)
NAD+ – supports ATP production and cellular repair when paired with SS-31
Glutathione – enhances antioxidant defense and detoxification during oxidative stress repair
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