BPC-157 5mg & TB-500 5mg

BPC-157 (Pentadecapeptide BPC-157) and TB-500 (synthetic thymosin beta-4 analog)
are laboratory peptides explored separately in preclinical models for roles in tissue protection and repair.
Together, they are often studied as a complementary blend: BPC-157 for endothelial/angiogenic and
matrix-oriented signaling; TB-500 for cytoskeletal dynamics, cell migration, and wound remodeling.

What They Are

• BPC-157: 15-amino-acid pentadecapeptide studied for effects on endothelial integrity,
  angiogenic signaling, nitric-oxide–linked pathways, and collagen matrix organization.
• TB-500: 43-amino-acid analog of thymosin β4, examined for actin binding/sequestration,
  cell motility, microtubule/cytoskeleton remodeling, and re-epithelialization in injury models.

Proposed Mechanisms (Preclinical)

Selected Research Highlights

• Skin/Wound Models: TB-500 (Tβ4) associated with faster re-epithelialization and contraction vs. controls in animal studies; small clinical datasets in chronic wounds have explored dose-response over multi-week protocols.
• Tendon/Ligament: TB-family peptides reported more organized collagen and improved mechanical properties post-injury; BPC-157 associated with fibroblast migration and collagen deposition in tendon explants.
• Muscle: BPC-157 explored in steroid-injury muscle models for functional restoration; TB-family peptides investigated for cytoskeletal remodeling and angiogenesis in cardiac ischemia models.
• Angiogenesis & Matrix: Both peptides studied for capillary density/neo-vessel formation and ECM organization under injury stressors.

Chemical Information

• BPC-157 — Formula: C₆₂H₉₈N₁₆O₂₂ · MW: 1419.5 g/mol
• TB-500 — Formula: C₂₁₂H₃₅₀N₅₆O₇₈S · MW: 4963 g/mol

Specifications

• Form: Lyophilized powders (research-grade)
• Purity: ≥99% (HPLC); COA per lot available
• Packaging: Sealed vials suitable for laboratory handling

Storage & Handling

• Store lyophilized vials in a cool, dry place, protected from light.
• After reconstitution: refrigerate at 2–8 °C.
• For long-term stability: store at −20 °C; avoid repeated freeze–thaw cycles.

Compliance Notice

For laboratory research use only. Not for human or veterinary use. Information is provided
for educational discussion of preclinical literature and does not constitute medical claims.