AICAR is an analog of adenosine monophosphate (AMP), a nucleotide that is considered to play an important role in cellular energy metabolism. It has been studied for its potential applications in research, particularly in reducing reperfusion injury after tissue ischemia and mitigating metabolic disorders. AICAR has been suggested to exert this potential by apparently activating AMP-activated protein kinase (AMPK), an enzyme that regulates various metabolic processes.
For research purposes only. This product is supplied exclusively for scientific laboratory research and analytical purposes. It is not intended for human or animal use, and must not be misused in any way that contravenes MHRA regulations or applicable laws.
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AICAR (5-Aminoimidazole-4-carboxamide-1-
β
D-ribofuranoside) is a potent AMP-activated protein kinase (AMPK) activator known as an "exercise mimetic." Its primary benefits include enhancing endurance and metabolism, increasing fatty acid oxidation, promoting weight loss, reducing metabolic inflammation, improving insulin sensitivity, and fostering mitochondrial biogenesis.
Key Potential Benefits of AICAR Peptide:
Improved Endurance and Metabolism: AICAR increases fatty acid oxidation and acts as an "exercise mimetic" by activating AMPK, which boosts mitochondrial production and energy metabolism in skeletal muscle.
Weight Loss and Fat Reduction:
Studies have shown that AICAR reduces abdominal fat and inhibits fat synthesis in adipose tissue.
Improved Insulin Sensitivity and Metabolic Health: It lowers blood glucose and insulin levels, improves glucose tolerance, and alleviates metabolic syndrome symptoms.
Enhanced Cardiovascular Function: AICAR may improve vascular integrity, reduce oxidative stress, and assist in regulating vascular tone and permeability.
Anti-inflammatory Effects: AICAR demonstrates significant anti-inflammatory effects in adipose tissue, which is beneficial for metabolic disorders.
Muscle Protection: It is studied for its ability to maintain muscle mass and reduce muscle decline associated with disease or aging.
Important Safety and Research Context
Performance Enhancement Prohibitions: Because of its potential to improve endurance without training, AICAR is prohibited by the World Anti-Doping Agency (WADA).
Experimental Compound: AICAR is primarily utilized in research contexts on mice and in laboratory settings; it is not approved for general human consumption.
www.usada.org +3
Disclaimer: This information is for research purposes only and does not constitute medical advice.
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